О враче
Место рождения: Анкара. Среднее образование — в частном лицее Тевфика Фикрета в Анкаре. Медицинское образование на медицинском факультете Университета Хаджеттепе завершено в 2006 г., включая работу в двух разных больницах во Франции по программе Эразмус. В том же году — начало ординатуры по неврологии на кафедре неврологии медицинского факультета Университета Хаджеттепе. С диссертацией «Активация RAGE и NF kappa-B при васкулитных нейропатиях и невоспалительных аксональных нейропатиях» получена премия Европейской неврологической академии «Премия молодого исследователя в области нейропатии». В 2011 г. по стипендии Европейской неврологической академии — продолжение работы по нейропатиям в Вюрцбургском университете (Германия) под руководством известного специалиста по нейропатической боли и нейропатиям проф. д-ра Claudia Sommer. В 2012 г. — завершение ординатуры по неврологии, затем обязательная государственная служба в Государственной больнице Анамура. В 2014–2016 гг. — завершение магистратуры по нейроиммунологии на кафедре клинических неврологических наук Института неврологических наук и психиатрии Университета Хаджеттепе. В 2015 г. — начало работы в должности доцента (yardımcı doçent) на кафедре неврологии Университета Хаджеттепе. В 2017 г. — звание «доцент по неврологии». В 2021–2022 гг. — клиническая и лабораторная работа по генной терапии нервно-мышечных заболеваний в Nationwide Children's Hospital (Огайо, США) совместно с проф. д-ром Jerry Mendell, разрабатывающим генную терапию спинальной мышечной атрофии (СМА) и мышечной дистрофии Дюшенна. В 2023 г. присвоено звание профессора неврологии. Работа по генетическим заболеваниям продолжается в рамках докторантуры на кафедре медицинской биологии. Член правления Рабочей группы по нервно-мышечным заболеваниям и нейропатической боли Турецкого неврологического общества. Помимо клинической работы в области клинических нервно-мышечных заболеваний на кафедре неврологии — выполнение диагностических биопсий мышц, нервов, мышц-нервов и кожи и участие в их патологической оценке в Исследовательской лаборатории нервно-мышечных заболеваний кафедры. Хорошее знание английского и французского языков.
Образование
- Devam EdiyorДокторантура — Институт медицинских наук, кафедра медицинской биологииУниверситет Хаджеттепе
- 2016Магистратура — Институт неврологических наук и психиатрииУниверситет Хаджеттепе
- 2006Медицинский факультет, неврологияУниверситет Хаджеттепе
- 2006Медицинский факультетУниверситет Хаджеттепе
- 1999Лицей Анкара Ёзел Тевфик Фикрет
Области специализации
Публикации
Источник: Система управления академическими данными Университета Хаджеттепе (AVESİS) · Все публикации (86) ↗
Articles 54
- Case Report: Steroid Responsive Pompe Like Inflammatory Myositis With Complete Recovery After Allogeneic HSCTInternational Journal of Rheumatic Diseases, cilt.29, sa.4, 2026 (SCI-Expanded, Scopus)
- Increased epidermal growth factor expression in amyotrophic lateral sclerosis patients: A potential protective mechanism against pressure ulcersTurk Noroloji Dergisi, cilt.32, sa.3, ss.230-236, 2026 (ESCI, Scopus)
- Detection of inflammation and glial cell-related biomarkers in adults with spinal muscular atrophy receiving nusinersen therapyNeurological Sciences, cilt.47, sa.1, 2026 (SCI-Expanded, Scopus)
- Random X chromosome inactivation in female Charcot-Marie-Tooth disease type X1: insights from sural nerve biopsy analysisBMC NEUROLOGY, cilt.25, sa.1, 2025 (SCI-Expanded, Scopus)
- Nivolumab- and ipilimumab-induced myositis, myasthenia gravis, and myocarditis in a patient with metastatic melanomaANTI-CANCER DRUGS, cilt.36, sa.7, 2025 (SCI-Expanded, Scopus)
- Transitioning From Nusinersen to Risdiplam for Spinal Muscular Atrophy in Clinical Practice: A Single-Center ExperienceMUSCLE & NERVE, cilt.71, sa.3, ss.414-421, 2025 (SCI-Expanded, Scopus)
- Clinical and laboratory remission with rituximab in anti-MuSK-positive myasthenia gravisIRISH JOURNAL OF MEDICAL SCIENCE, cilt.193, ss.2989-2994, 2024 (SCI-Expanded, Scopus)
- A novel pathogenic PTRH2 variant indicates seizure association with protein-truncating variants in Infantile-Onset Multisystem Neurologic, Endocrine and Pancreatic Disease (IMNEPD)EUROPEAN JOURNAL OF HUMAN GENETICS, ss.1494, 2024 (SCI-Expanded, Scopus)
- Effect of Follicular T Helper and T Helper 17 Cells-Related Molecules on Disease Severity in Patients with Myasthenia GravisEUROPEAN NEUROLOGY, cilt.87, sa.5-6, ss.223-229, 2024 (SCI-Expanded, Scopus)
- A novel pathogenic PTRH2 variant indicates seizure association with protein-truncating variants in Infantile-Onset Multisystem Neurologic, Endocrine and Pancreatic Disease (IMNEPD)EUROPEAN JOURNAL OF HUMAN GENETICS, ss.1494, 2024 (SCI-Expanded, Scopus)
- Differentiating recurrent Guillain-Barre syndrome and acute-onset chronic inflammatory polyneuropathy: literature reviewACTA NEUROLOGICA BELGICA, cilt.124, ss.1467-1475, 2024 (SCI-Expanded, Scopus)
- VARIABLE PHENOTYPE IN FEMALES WITH HETEROZYGOUS GJB1 MUTATIONJOURNAL OF THE PERIPHERAL NERVOUS SYSTEM, 2024 (SCI-Expanded, Scopus)
- Recurrent simultaneous central nervous system demyelination with possible peripheral demyelination / nodopathy in a seronegative patientIDEGGYOGYASZATI SZEMLE-CLINICAL NEUROSCIENCE, cilt.77, sa.9-10, ss.357-360, 2024 (SCI-Expanded, Scopus)
- Nusinersen for adults with spinal muscular atrophyNeurological Sciences, cilt.44, sa.7, ss.2393-2400, 2023 (SCI-Expanded, Scopus)
- The evaluation of small fibers in multiple sclerosisMultiple Sclerosis and Related Disorders, cilt.72, 2023 (SCI-Expanded, Scopus)
- Two distinct skeletal muscle microRNA signatures revealing the complex mechanism of sporadic ALSACTA NEUROLOGICA BELGICA, cilt.122, sa.6, ss.1499-1509, 2022 (SCI-Expanded, Scopus)
- Comprehensive evaluation of velopharyngeal function in myasthenia gravis patientsACTA NEUROLOGICA BELGICA, cilt.122, sa.5, ss.1229-1236, 2022 (SCI-Expanded, Scopus)
- Identifying a Cut-off Point for Timed Up and Go Test in Neuromuscular DiseasesTURKISH JOURNAL OF NEUROLOGY, cilt.28, sa.1, ss.6-9, 2022 (ESCI, Scopus, TRDizin)
- The functional and structural evaluation of small fibers in asymptomatic carriers of TTR p.Val50Met (Val30Met) mutationNEUROMUSCULAR DISORDERS, cilt.32, sa.1, ss.50-56, 2022 (SCI-Expanded, Scopus)
- Eculizumab in refractory generalized myasthenia gravis previously treated with rituximab: subgroup analysis of REGAIN and its extension studyMuscle and Nerve, cilt.64, sa.6, ss.662-669, 2021 (SCI-Expanded, Scopus)
- One Disease with two Faces: Semidominant Inheritance of a Novel HTRA1 Mutation in a Consanguineous FamilyJOURNAL OF STROKE & CEREBROVASCULAR DISEASES, cilt.30, sa.9, 2021 (SCI-Expanded, Scopus)
- The evaluation of small fibers in asymptomatic carriers of Val30Met mutation: Results of three years follow-upJOURNAL OF THE PERIPHERAL NERVOUS SYSTEM, cilt.26, sa.3, ss.379, 2021 (SCI-Expanded, Scopus)
- Biologia Futura: the importance of 3D organoids-a new approach for research on neurological and rare diseasesBIOLOGIA FUTURA, cilt.72, sa.3, ss.281-290, 2021 (SCI-Expanded, Scopus)
- A Rare Cause of Dystonia: Spinal MeningiomaTURKISH JOURNAL OF NEUROLOGY, cilt.27, sa.2, ss.215-216, 2021 (ESCI, Scopus, TRDizin)
- Reliability and Validity of Turkish Myasthenia Gravis-Activities of Daily Living ScaleOTJR-OCCUPATION PARTICIPATION AND HEALTH, cilt.41, sa.2, ss.101-107, 2021 (SSCI, Scopus)
- Psychosocial Adjustment and Adherence to Medication in Patients with Myasthenia GravisGAZI MEDICAL JOURNAL, cilt.32, sa.3, ss.371-376, 2021 (ESCI, Scopus)
- Organelle Positioning in Neurons and Skeletal Muscle CellsGAZI MEDICAL JOURNAL, cilt.32, ss.341-347, 2021 (ESCI, Scopus)
- Consistent improvement with eculizumab across muscle groups in myasthenia gravisAnnals of Clinical and Translational Neurology, cilt.7, sa.8, ss.1327-1339, 2020 (SCI-Expanded, Scopus)
- Trigeminal sensory-motor neuropathy in a patient with mixed connective tissue disease and review of the literatureNEUROLOGICAL SCIENCES AND NEUROPHYSIOLOGY, cilt.37, sa.3, ss.148-151, 2020 (SCI-Expanded, Scopus, TRDizin)
- A Novel Amplification-Refractory Mutation System-PCR Strategy to Screen MT-TL1 Pathogenic Variants in Patient RepositoriesGENETIC TESTING AND MOLECULAR BIOMARKERS, cilt.24, sa.3, ss.165-170, 2020 (SCI-Expanded, Scopus)
- Giant cell myositis associated with myasthenia gravis and thymomaNEUROLOGICAL SCIENCES AND NEUROPHYSIOLOGY, cilt.36, sa.4, ss.236-237, 2019 (SCI-Expanded, Scopus, TRDizin)
- Long-term safety and efficacy of eculizumab in generalized myasthenia gravisMuscle and Nerve, cilt.60, sa.1, ss.14-24, 2019 (SCI-Expanded, Scopus)
- Laboratory diagnosis of metachromatic leukodystrophy requires more than arylsulfatase A assayFEBS OPEN BIO, cilt.9, ss.199, 2019 (SCI-Expanded, Scopus)
- Two sisters with anti-MuSK-positive myasthenia gravisCLINICAL NEUROLOGY AND NEUROSURGERY, cilt.182, ss.17-18, 2019 (SCI-Expanded, Scopus)
- Establishment of primary myoblast cell cultures from cryopreserved skeletal muscle biopsies to serve as a tool in related research & development studiesJOURNAL OF THE NEUROLOGICAL SCIENCES, cilt.393, ss.100-104, 2018 (SCI-Expanded, Scopus)
- Ocular surface alterations and in vivo confocal microscopic characteristics of corneas in patients with myasthenia gravisEUROPEAN JOURNAL OF OPHTHALMOLOGY, cilt.28, sa.5, ss.541-546, 2018 (SCI-Expanded, Scopus)
- The histopathological evaluation of small fiber neuropathy in patients with vitamin B12 deficiencyACTA NEUROLOGICA BELGICA, cilt.118, sa.3, ss.405-410, 2018 (SCI-Expanded, Scopus)
- ERLIN1 mutations cause teenage-onset slowly progressive ALS in a large Turkish pedigreeEUROPEAN JOURNAL OF HUMAN GENETICS, cilt.26, sa.5, ss.745-748, 2018 (SCI-Expanded, Scopus)
- Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre studyThe Lancet Neurology, cilt.16, sa.12, ss.976-986, 2017 (SCI-Expanded, Scopus)
- Myophosphorylase (PYGM) mutations determined by next generation sequencing in a cohort from Turkey with McArdle diseaseNEUROMUSCULAR DISORDERS, cilt.27, sa.11, ss.997-1008, 2017 (SCI-Expanded, Scopus)
- CELLULAR INFILTRATES IN SKIN AND SURAL NERVE OF PATIENTS WITH POLYNEUROPATHIESMUSCLE & NERVE, cilt.55, sa.6, ss.884-893, 2017 (SCI-Expanded, Scopus)
- New mutations and genotype-phenotype correlation in late-onset Pompe patientsACTA NEUROLOGICA BELGICA, cilt.117, sa.1, ss.269-275, 2017 (SCI-Expanded, Scopus)
- Single-pulse Transcranial Magnetic Stimulation in Amyotrophic Lateral Sclerosis: Experience of a single institutionJOURNAL OF NEUROLOGICAL SCIENCES-TURKISH, cilt.34, sa.1, ss.70-75, 2017 (SCI-Expanded, Scopus, TRDizin)
- Dysferlinopathy: A Case Report and Literature UpdateISTANBUL MEDICAL JOURNAL, cilt.17, sa.4, ss.136-140, 2016 (ESCI, TRDizin)
- Autoimmune stormEUROPEAN JOURNAL OF NEUROLOGY, cilt.23, ss.437, 2016 (SCI-Expanded, Scopus)
- The evaluation of small fibres in asymptomatic patients with Val30Met mutationEUROPEAN JOURNAL OF NEUROLOGY, cilt.23, ss.231, 2016 (SCI-Expanded, Scopus)
- Spinal muscular atrophy type III: Molecular genetic characterization of Turkish patientsEUROPEAN JOURNAL OF MEDICAL GENETICS, cilt.58, sa.12, ss.654-658, 2015 (SCI-Expanded, Scopus)
- The Activation of RAGE and NF-KB in Nerve Biopsies of Patients with Axonal and Vasculitic NeuropathyNOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY, cilt.52, sa.3, ss.279-282, 2015 (SCI-Expanded, Scopus, TRDizin)
- Three Turkish families with different transthyretin mutationsNEUROMUSCULAR DISORDERS, cilt.25, sa.9, ss.686-692, 2015 (SCI-Expanded, Scopus)
- Voltage gated calcium channel antibody-related neurological diseases.World journal of clinical cases, cilt.3, ss.293-300, 2015 (SCI-Expanded, Scopus)
- CUTANEOUS ACTIVATION OF RAGE IN NONSYSTEMIC VASCULITIC AND DIABETIC NEUROPATHYMUSCLE & NERVE, cilt.50, sa.3, ss.377-383, 2014 (SCI-Expanded, Scopus)
- The Course of Myasthenia Gravis with Systemic Lupus ErythematosusEUROPEAN NEUROLOGY, cilt.72, ss.326-329, 2014 (SCI-Expanded, Scopus)
- Myasthenia Gravis; Single Entity, Variable Clinical Features: Ten Years of Clinical Experience in a Tertiary Care Center Ten Years Clinical Experience of a Tertiary Care CenterJOURNAL OF NEUROLOGICAL SCIENCES-TURKISH, cilt.30, sa.1, ss.135-143, 2013 (SCI-Expanded, Scopus, TRDizin)
- 'Jaw clenching' in anti-Ri - Antibody-associated paraneoplastic syndromePARKINSONISM & RELATED DISORDERS, cilt.19, sa.1, ss.132-133, 2013 (SCI-Expanded, Scopus)
Conference papers 32
- The effect and challenges of nusinersen treatment in adult spinal muscular atrophy patients - preliminary results6th Congress of the European-Academy-of-Neurology (EAN), ELECTR NETWORK, 23 - 26 Mayıs 2020, cilt.27, ss.625, (Özet Bildiri)
- Multimodal Assessment Of Intensive Care Unit-Acquired Weakness (ICU-AW) In Severe Acute Stroke Patients2019 PNS Meeting, 22 - 26 Haziran 2019, (Özet Bildiri)
- Erişkin Kas Hastalarında Fiziksel Aktiviteyi Objektif ve Subjektif Olarak Değerlendiren Yöntemlerin KarşılaştırılmasıTND II. Nöromusküler Hastalıklar Kongresi, İzmir, Türkiye, 19 - 21 Nisan 2019, (Özet Bildiri)
- Nusinersen İlacı İçin Başvuruda Bulunan Spinal Musküler Atrofi Tip 2 ve Tip 3 Tanılı Hastaların ProfiliTND II. Nöromusküler Hastalıklar Kongresi, İzmir, Türkiye, 19 - 21 Nisan 2019, (Özet Bildiri)
- Erişkin Nöromusküler Hastalarda Düşme Öyküsünün AktiviteLimitasyonu ve Gövde Bozukluk Düzeyi ile İlişkisinin İncelenmesiTND II. Nöromusküler Hastalıklar Kongresi, İzmir, Türkiye, 19 - 21 Nisan 2019, (Özet Bildiri)
- Erişkin Kas Hastalarında Fiziksel Aktivite ile İlişkili Faktörlerin BelirlenmesiTND II. Nöromusküler Hastalıklar Kongresi, İzmir, Türkiye, 19 - 21 Nisan 2019, (Özet Bildiri)
- Kas Hastalarında Farklı Yüksekliklerden Oturmadan Ayağa Kalkma Sırasında Uyluk Kaslarının Aktivasyon Seviyelerinin İncelenmesiTND II. Nöromusküler Hastalıklar Kongresi, İzmir, Türkiye, 19 - 21 Nisan 2019, (Özet Bildiri)
- Nöroloji Yoğun Bakım Ünitesi'ndeki İnme Hastalarında Yoğun Bakım Ünitesinde Edinilmiş Güçsüzlüğün (YBÜ-EG) Multimodal İncelemesi35. ULUSAL KLİNİK NÖROFİZYOLOJİ EEG-EMG KONGRESİ, Muğla, Türkiye, 3 - 07 Nisan 2019, (Özet Bildiri)
- Differentially Expressed microRNA Profile in Skeletal Muscle Tissue of Sporadic ALS Patients71st Annual Meeting of the American-Academy-of-Neurology (AAN), Pennsylvania, Amerika Birleşik Devletleri, 4 - 10 Mayıs 2019, cilt.92, (Özet Bildiri)
- The expression of epidermal growth factor (EGF) and keratinocyte growth factor (KGF) in skin biopsy of amyotrophic lateral sclerosis patients70th Annual Meeting of the American-Academy-of-Neurology (AAN), Los-Angeles, Şili, 21 - 27 Nisan 2018, cilt.90, (Özet Bildiri)
- Myastenia gravis hastalarında altı dakika yürüyüş testinin kullanımı1. Kardiyopulmoner Rehabilitasyon Kongresi, Türkiye, 22 - 25 Kasım 2017, cilt.29, (Özet Bildiri)
- Myastenia gravisli bireylerde fizisel kapasitenin solunum fonksiyonları, yaşam kalitesi ve özür seviyesi ile ilişkisi53. Ulusal Nöroloji Kongresi, Türkiye, 24 - 30 Kasım 2017, (Özet Bildiri)
- Myastenia gravis hastalarının hastalığa psikososyal uyumu ve ilaç uyumlarının belirlenmesi.. 5. Uluslararası, 16. Ulusal Hemşirelik Kongresi, Ankara, Türkiye, 5 - 08 Kasım 2017, (Özet Bildiri)
- VECTOR-BORNE VIRAL INFECTIONS IN GUILLAIN BARRE SYNDROME PATIENTSPeripheral-Nerve-Society Meeting, Sitges, İspanya, 8 - 12 Temmuz 2017, cilt.22, ss.349-350, (Özet Bildiri)
- Acute myopathy in patients who are using short-term and low-dose systemic glucucorticoids: Preliminary findings16th European Congress of Internal Medicine, 31 Ağustos - 02 Eylül 2017, (Özet Bildiri)
- Recurrent peripheral and central demyelination in a seronegative patientperipheral Nerve Society Meeting, 8 Temmuz - 13 Eylül 2017, (Özet Bildiri)
- Low levels of SMN cause alterations in microtubule associated protein 1b21th Annual Spinal Muscular Atrophy Researcher Meeting, Orlando, Amerika Birleşik Devletleri, 29 Haziran - 02 Temmuz 2017, (Özet Bildiri)
- The Histopathological Evaluation of Small Fiber Neuropathy in Patients with Vitamin B12 Deficiency68th Annual Meeting of the American-Academy-of-Neurology (AAN), Vancouver, Kanada, 15 - 21 Nisan 2016, cilt.86, (Özet Bildiri)
- Myastenia Gravis de Velofaringeal Fonksiyonun Araştırılması4. YUTMA BOZUKLUKLARI KONGRESİ, Türkiye, 19 - 21 Kasım 2015, (Özet Bildiri)
- A RARE CAUSE OF LUMBOSACRAL PLEXOPATHY: BLADDER DIVERTICULUMBiennial Meeting of the Peripheral-Nerve-Society, Quebec, Kanada, 27 Haziran - 02 Temmuz 2015, cilt.20, ss.166-167, (Özet Bildiri)
- A HEREDITARY AMYLOID POLYNEUROPATHY FAMILY DUE TO VAL30MET MUTATION WITH AN INDEX CASE PRESENTED LIKE CIDPBiennial Meeting of the Peripheral-Nerve-Society, Quebec, Kanada, 27 Haziran - 02 Temmuz 2015, cilt.20, ss.103, (Özet Bildiri)
- A novel mutation in the HTRA1 gene in a Turkish family with CARASIL1st Congress of the European-Academy-of-Neurology, Berlin, Almanya, 20 - 23 Haziran 2015, cilt.22, ss.258, (Özet Bildiri)
- The incidence of Pompe disease in patients with vacuolar myopathy: a pilot study of a tertiary care center1st Congress of the European-Academy-of-Neurology, Berlin, Almanya, 20 - 23 Haziran 2015, cilt.22, ss.623, (Özet Bildiri)
- The time course of pseudo-conduction blocks in a patient with vasculitic neuropathyJoint Congress of European Neurology, İstanbul, Türkiye, 31 Mayıs - 03 Haziran 2014, cilt.261, (Özet Bildiri)
- Three families with hereditary amyloid polyneuropathy with three different mutationsJoint Congress of European Neurology, İstanbul, Türkiye, 31 Mayıs - 03 Haziran 2014, cilt.261, (Özet Bildiri)
- NUSİNERSEN TEDAVİSİ ALAN ERİŞKİN SPİNAL MUSKÜLER ATROFİ HASTALARINDA İNFLAMASYON VE GLİAL HÜCRE İLİŞKİLİ BİYOBELİRTEÇLERİN TESPİTİ
- MİYASTENİK KRİZ İLE BAŞVURAN HASTALARDA YARDIMCI FOLİKÜLER T HÜCRE (TFH) VE YARDIMCI T HÜCRE 17 (TH17) İLİŞKİLİ SİTOKİNLERİN TEDAVİ ÖNCESİ VE SONRASI DEĞİŞKENLİĞİ
- Evaluation of the Role of Glial Factors in the Pathogenesis of Spinal Muscular Atrophy
- Serum Cytokines Levels in Patients with Myasthenia Gravis and Their Changes After Treatment
- MME MUTASYONUNA BAĞLI DEMİYELİNİZAN NÖROPATİ
- The evaluation of small fibers in asymptomatic carriers of Val30Met mutation: Results of three years follow-up
- Multimodal Assessment of Intensive Care Unit- Acquired Weakness in Severe Stroke Patients
Контакты
- Телефон
- 0312 305 18 06
- Отделение
- Неврология, Больница для взрослых
- Владение языками
- Английский на хорошем уровне, Французский
Последнее обновление:
