О враче
Окончила англоязычный медицинский факультет Университета Хаджеттепе в 2000 году. Ординатуру по психиатрии, начатую в том же году на кафедре психиатрии Университета Башкент, завершила в 2005 году. Сразу после этого начала докторантуру по фундаментальным неврологическим наукам (Neuroscience) в Институте неврологических наук и психиатрии Университета Хаджеттепе; диссертационную часть докторской работы завершила в лаборатории проф. д-ра Huda Akil в Мичиганском университете (США), куда ездила на 2 года. Докторскую степень получила в 2009 году.
В 2005 году получила премию поддержки проектов Общества исследований мозга и премию поддержки исследовательских проектов Турецкого психиатрического общества. В 2007 году стала стипендиаткой Novartis Foundation и в течение 3 месяцев работала в Институте молекулярной и поведенческой нейронауки Мичиганского университета. Эти исследования продолжила как стипендиатка Интегрированной докторской исследовательской программыTÜBA, полученной в 2007 году. В 2011 году получила поддержку проекта Tübitak по развитию карьеры молодых исследователей.
В настоящее время продолжает работу в Институте неврологических наук и психиатрии и на кафедре психиатрии.Окончила англоязычный медицинский факультет Университета Хаджеттепе в 2000 году. Ординатуру по психиатрии, начатую в том же году на кафедре психиатрии Университета Башкент, завершила в 2005 году. Сразу после этого начала докторантуру по фундаментальным неврологическим наукам (Neuroscience) в Институте неврологических наук и психиатрии Университета Хаджеттепе; диссертационную часть докторской работы завершила в лаборатории проф. д-ра Huda Akil в Мичиганском университете (США), куда ездила на 2 года. Докторскую степень получила в 2009 году.
В 2005 году получила премию поддержки проектов Общества исследований мозга и премию поддержки исследовательских проектов Турецкого психиатрического общества. В 2007 году стала стипендиаткой Novartis Foundation и в течение 3 месяцев работала в Институте молекулярной и поведенческой нейронауки Мичиганского университета. Эти исследования продолжила как стипендиатка Интегрированной докторской исследовательской программыTÜBA, полученной в 2007 году. В 2011 году получила поддержку проекта Tübitak по развитию карьеры молодых исследователей.
В настоящее время продолжает работу в Институте неврологических наук и психиатрии и на кафедре психиатрии.
Образование
- ПсихиатрияПсихиатрия
- 2009Докторантура — Фундаментальные неврологические наукиУниверситет Хаджеттепе
- 2000Медицинский факультет с обучением на английском языкеУниверситет Хаджеттепе
- 1994Колледж TED Кайсери
Области специализации
Публикации
Источник: Система управления академическими данными Университета Хаджеттепе (AVESİS) · Все публикации (64) ↗
Articles 33
- Biallelic ATG9B Variants Define a Novel Autophagy-Related Neurodevelopmental Disorder with Cerebellar AtaxiaGenes, cilt.17, sa.6, 2026 (SCI-Expanded, Scopus)
- Twelve-Month Use of Mental Health Services: Results from the World Mental Health Türkiye Survey Türkiye’de On İki Aylık Ruh Sağlığı Hizmeti Kullanımı: Türkiye Ruh Sağlığı Profili-2 Araştırması SonuçlarıTurk Psikiyatri Dergisi, cilt.37, ss.192-204, 2026 (SSCI, Scopus)
- Prevalence, Persistence, and Severity of 12-Month and 30-Day DSM-5 Disorders in the Turkish World Mental Health Survey Türkiye Ruh Sağlığı Profili-2 Araştırması’nda 12 Aylık ve 30 Günlük DSM-5 Bozukluklarının Yaygınlığı, Süregenliği ve ŞiddetiTurk Psikiyatri Dergisi, cilt.37, ss.180-191, 2026 (SSCI, Scopus)
- Sex-Specific Reversal of Stress-Induced Depressogenic Behaviors by Inhibition of HMGB1, TLR4, and NF-κB SignalingMolecular Neurobiology, cilt.63, sa.1, 2026 (SCI-Expanded, Scopus)
- Layer-specific input to medial prefrontal cortex is linked to stress susceptibilityTRANSLATIONAL PSYCHIATRY, cilt.15, sa.1, 2025 (SCI-Expanded, Scopus)
- Attention-related impairment and contributing neuroinflammatory signalling in the prefrontal cortex of perinatal nicotine-exposed miceACTA NEUROPSYCHIATRICA, cilt.37, 2025 (SCI-Expanded, Scopus)
- Morphological Correlates of Behavioral Variation in Autism Spectrum Disorder Groups in A Maternal Immune Activation ModelNOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY, cilt.61, sa.3, ss.195-201, 2024 (SCI-Expanded, Scopus, TRDizin)
- FGF2 gene's antisense protein, NUDT6, plays a depressogenic role by promoting inflammation and suppressing neurogenesis without altering FGF2 signallingJournal of Physiology, cilt.602, sa.7, ss.1427-1442, 2024 (SCI-Expanded, Scopus)
- Cortical spreading depression can be triggered by sensory stimulation in primed wild type mouse brain: a mechanistic insight to migraine aura generationJOURNAL OF HEADACHE AND PAIN, cilt.23, sa.1, 2022 (SCI-Expanded, Scopus)
- NF-KB and HMGB1 Differentially Mediate Effects of Acute Predator Stress on Anhedonia and Behavioral DespairBIOLOGICAL PSYCHIATRY, cilt.91, sa.9, 2022 (SCI-Expanded, Scopus)
- The Role of NUDT6 and S100A9 as New Molecular Players in Hippocampus, Basolateral Amygdala and Prefrontal Cortex in a Post-Traumatic Stress Disorder (PTSD) ModelBIOLOGICAL PSYCHIATRY, cilt.91, sa.9, 2022 (SCI-Expanded, Scopus)
- cAMP/PKA-CREB-BDNF signaling pathway in hippocampus of rats subjected to chemically-induced phenylketonuriaMETABOLIC BRAIN DISEASE, cilt.37, sa.2, ss.545-557, 2022 (SCI-Expanded, Scopus)
- Ion Channel Dysfunction and Neuroinflammation in Migraine and DepressionFRONTIERS IN PHARMACOLOGY, cilt.12, 2021 (SCI-Expanded, Scopus)
- Brain glycogen metabolism: A possible link between sleep disturbances, headache and depressionSLEEP MEDICINE REVIEWS, cilt.59, 2021 (SCI-Expanded, Scopus)
- The Effects of P2X7 Antagonism on Neuroinflammation Following Optogenetically-Triggered Cortical Spreading DepressionJOURNAL OF HEADACHE AND PAIN, cilt.22, sa.SUPPL 1, ss.14, 2021 (SCI-Expanded, Scopus)
- The Effects of P2X7 Antagonism on Neuroinflammation Following Optogenetically-Triggered Cortical Spreading DepressionCEPHALALGIA, cilt.41, sa.1_SUPPL, ss.20, 2021 (SCI-Expanded, Scopus)
- The Effect of P2X7 Antagonism on Subcortical Spread of Optogenetically-Triggered Cortical Spreading DepressionEUROPEAN JOURNAL OF NEUROLOGY, cilt.28, ss.308, 2021 (SCI-Expanded, Scopus)
- Effect of FGF-AS Modulation on Neurogenesis in Rat HippocampusBIOLOGICAL PSYCHIATRY, cilt.89, sa.9, 2021 (SCI-Expanded, Scopus)
- Nuclear expansion and pore opening are instant signs of neuronal hypoxia and can identify poorly fixed brainsSCIENTIFIC REPORTS, cilt.8, 2018 (SCI-Expanded, Scopus)
- Stress modulates cortical excitability via alpha-2 adrenergic and glucocorticoid receptors: As assessed by spreading depressionEXPERIMENTAL NEUROLOGY, cilt.307, ss.45-51, 2018 (SCI-Expanded, Scopus)
- Striatal Neurotransmitter Release-related Presynaptic Proteins in L-dopa Induced Dyskinesia in a Model of ParkinsonismNOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY, cilt.55, sa.1, ss.73-79, 2018 (SCI-Expanded, Scopus, TRDizin)
- Brain Peptides for the Treatment of Neuropsychiatric DisordersCURRENT PHARMACEUTICAL DESIGN, cilt.24, sa.33, ss.3905-3917, 2018 (SCI-Expanded, Scopus)
- Inadequate Brain Glycogen or Sleep Increases Spreading Depression SusceptibilityANNALS OF NEUROLOGY, cilt.83, sa.1, ss.61-73, 2018 (SCI-Expanded, Scopus)
- Cognitive Dysfunctions in Posttraumatic Stress DisorderTURK PSIKIYATRI DERGISI, cilt.28, sa.2, ss.124-131, 2017 (SSCI, Scopus, TRDizin)
- A Simple Extraction Procedure for HPLC Analysis of Fluoxetine in Rat Plasma SamplesCURRENT PHARMACEUTICAL ANALYSIS, cilt.13, sa.1, ss.80-84, 2017 (SCI-Expanded, Scopus)
- Dysregulated fibroblast growth factor (FGF) signaling in neurological and psychiatric disordersSEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, cilt.53, ss.136-143, 2016 (SCI-Expanded, Scopus)
- Posttraumatic Growth After Earthquake Trauma is Predicted by Executive Functions A Pilot StudyJOURNAL OF NERVOUS AND MENTAL DISEASE, cilt.202, sa.12, ss.859-863, 2014 (SCI-Expanded, SSCI, Scopus)
- Effects of Acute and Chronic Electroconvulsive Shocks on Glycogen Synthase Kinase 3[beta] Level and Phosphorylation in MiceJOURNAL OF ECT, cilt.29, sa.4, ss.261-266, 2013 (SCI-Expanded, SSCI, Scopus)
- The role of fibroblast growth factor antisense in modulation of affective behaviourEUROPEAN NEUROPSYCHOPHARMACOLOGY, cilt.23, 2013 (SCI-Expanded, Scopus)
- Spreading Depression Triggers Headache by Activating Neuronal Panx1 ChannelsSCIENCE, cilt.339, sa.6123, ss.1092-1095, 2013 (SCI-Expanded, Scopus)
- Psychiatric Disorders and EpigeneticsTURK PSIKIYATRI DERGISI, cilt.23, sa.2, ss.130-140, 2012 (SSCI, Scopus, TRDizin)
- Short-Hairpin RNA Silencing of Endogenous Fibroblast Growth Factor 2 in Rat Hippocampus Increases Anxiety BehaviorBIOLOGICAL PSYCHIATRY, cilt.69, sa.6, ss.534-540, 2011 (SCI-Expanded, Scopus)
- Memory and prefrontal functions in earthquake survivors: differences between current and past post-traumatic stress disorder patientsACTA PSYCHIATRICA SCANDINAVICA, cilt.119, sa.1, ss.35-44, 2009 (SCI-Expanded, SSCI, Scopus)
Conference papers 31
- Kronik stresin bellek üzerine etkileri dişi ile erkek farelerde farklı mı?Ulusal Sinirbilim Kongresi, Türkiye, 07 Kasım 2020, (Özet Bildiri)
- The Role of AAV-Mediated FGF-AS Overexpression in Neuroinflammation in Rat Hippocampus75th Annual Scientific Convention and Meeting of the Society-of-Biological-Psychiatry (SOBP), New York, Amerika Birleşik Devletleri, 30 Nisan - 02 Mayıs 2020, cilt.87, (Özet Bildiri)
- Changes in hippocampal cholinergic system in an experimental rat Phenylketonuria modelXVIth International Symposium on Cholinergic Mechanisms (ISCM-XVI), Rekhovot, İsrail, 8 - 13 Aralık 2019, (Özet Bildiri)
- The role of 12/15 lipoxygenase inhibition on stroke induced neuroinflammationSociety for Neuroscience, 19 - 23 Ekim 2019, (Özet Bildiri)
- Inhibition of retinal and cerebral microvascular glycogen utilization promotes capillary constrictions in mice29th International Symposium on Cerebral Blood Flow, Metabolism and Function / 14th International Conference on Quantification of Brain Function with PET (BRAIN and BRAIN Pet), Yokohama, Japonya, 4 - 07 Temmuz 2019, cilt.39, ss.288-289, (Özet Bildiri)
- Cortical spreading depression induces expression of BDNF and pro-BDNF proteins, which may impact neuroinflammation29th International Symposium on Cerebral Blood Flow, Metabolism and Function / 14th International Conference on Quantification of Brain Function with PET (BRAIN and BRAIN Pet), Yokohama, Japonya, 4 - 07 Temmuz 2019, cilt.39, ss.519-520, (Özet Bildiri)
- Molecular Motor Mechanism of Contraction in Central Nervous System Pericytes17. Ulusal Sinirbilim Kongresi, Trabzon, Türkiye, 04 Nisan 2019, (Özet Bildiri)
- Merkezi sinir sistemi perisitlerinde kasılmanın moleküler mekanizması17. Ulusal Sinirbilim Kongresi, Türkiye, 4 - 07 Nisan 2019, (Özet Bildiri)
- Hippocampal FGF-antisense overexpression increase depression-like behaviour in the rat31st Congress of the European-College-of-Neuropsychopharmacology (ECNP), Barcelona, İspanya, 6 - 09 Ekim 2018, cilt.29, (Özet Bildiri)
- Lipooksijenaz inhibisyonunun kalıcı serebral iskemi modelinde oluşan nöroinflamasyon üzerine etkisi16. ULUSAL SİNİRBİLİM KONGRESİ, 20-23 Mayıs 2018, İTÜ Ayazağa Kampüsü, İstanbul., İstanbul, Türkiye, 20 - 23 Mayıs 2018, (Özet Bildiri)
- Effect of Hippocampal Overexpression of a Natural Antisense protein, FGFAS, on Learning and Memory73rd Annual Meeting of Society of Bİological Paychiatry, 10 Mayıs 2018, (Özet Bildiri)
- Migren Araştırmaları için yeni bir kortikal yayılan depresyona yatkınlık modeli: Na-K ATPaz A-2 RNA İnterferansı53. Ulusal Nöroloji Kongresi, Türkiye, 25 - 29 Kasım 2017, (Özet Bildiri)
- Fluorescent biomarkers as reporters of poor quality transcardial perfusion-fixation in frozen brain sections: A much needed tool for experimental neuroscience.Society for Neuroscience Annual Meeting, 11 - 15 Kasım 2017, (Özet Bildiri)
- 12/15 lipoxygenase inhibition suppresses neuroinflammation in a thrombotic permanent cerebral ischemia model23rd World Congress of Neurology (WCN), Kyoto, Japonya, 16 - 21 Eylül 2017, cilt.381, ss.863-864, (Özet Bildiri)
- 12/15 Lipoxygenase Inhibition Supresses Neuroinflammation in a Thrombotic Permanent Cerebral Ischemia ModelWCN 2017, Kyoto, Japonya, 16 - 22 Eylül 2017, cilt.381, ss.863-864, (Özet Bildiri)
- 12/15 Lipoxygenase Inhibition Suppresses Neuroinflammation in aThrombotic Permanent Cerebral Ischemia Model.XXIII World Congress of Neurology, 16 - 21 Eylül 2017, (Özet Bildiri)
- FGF-AS Overexpression in Medial Prefrontal Cortex Regulates Anxiety-like Behavior in Rats30th ECNP Congress, 2 - 05 Eylül 2017, (Özet Bildiri)
- The Effect of NUDT6 Expression on Contextual Learning Assessed by Passive Avoidance TestAnnual Meeting of American Psychiatric Association, 20 - 24 Mayıs 2017, (Özet Bildiri)
- Investigation of a marker for the quality of transcardial perfusion in frozen brain sections is mice15. Ulusal Sinirbilim Kongresi, 7 - 10 Mayıs 2017, cilt.11, ss.35, (Özet Bildiri)
- Lipoksijenaz İnhibisyonunun Akut Geçici Serebral İskemi/Rekanalizasyon Modelinde Gelişen Nöroinflamasyona Etkisi15.Ulusal Sinirbilim Kongresi, 7 - 10 Mayıs 2017, (Özet Bildiri)
- Role of a Natural Antisense Transcript, FGF2-AS, in Affective Behavior72nd Annual Scientific Convention and Meeting of the Society-of-Biological-Psychiatry (SOBP), California, Amerika Birleşik Devletleri, 18 - 20 Mayıs 2017, cilt.81, (Özet Bildiri)
- Cortical spreading depression can be triggered by photic stimulation in susceptible mouse brainFENS, 2 - 06 Temmuz 2016, (Özet Bildiri)
- Depresyon nörobiyolojisinde yeni bir molekül GFG50. Ulusal Psikiyatri Kongresi, Antalya, Türkiye, 12 - 16 Kasım 2014, cilt.25, ss.5-6
- The fole of FGF2 AS in stress and depression like behavior in ratsAnnual Meeting of Society for Neuroscience, San Diego, Amerika Birleşik Devletleri, 9 - 13 Kasım 2013
- Striatal neurotransmitter release-related presynaptic proteins in L-dopa induced dyskinesia in 6-hydroxydopamine model of parkinsonism14th International Congress of Parkinson’s Disease and Movement Disorders, Buenos Aires, Arjantin, 13 - 17 Haziran 2010, (Özet Bildiri)
- Tenses can have different effects on declarative processes22nd Congress of the European-College-of-Neuropsychopharmacology, İstanbul, Türkiye, 12 - 16 Eylül 2009, cilt.19, (Özet Bildiri)
- Sıçanda L-dopa diskinezi modelinde striatal presinaptik proteinlerin ekspresyonu43. Ulusal Nöroloji Kongresi, Antalya, Türkiye, 10 - 15 Kasım 2007, cilt.13, ss.89, (Özet Bildiri)
- Effects of chronic electroconvulsive shock on glycogen synthase kinase 3 beta protein level and phosphorylation pattern in hippocampus and frontal lobe15. CINP (International College of Neuropsychopharmacology) Congress, Şikago, Amerika Birleşik Devletleri, 9 - 13 Temmuz 2006, cilt.9, ss.178
- Cerebral peri-microvascular glycogen utilization has a role in endothelium-pericyte interaction in mice
- Resolution of neuroinflammation triggered by cortical spreading depression
- NUDT6 Aşırı İfadesi ile Dendritik Çıkıntı Sayısı İlişkisi
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