About
Assoc. Prof. Dr. Cem Şimşek is a faculty member in the Division of Gastroenterology, Hacettepe University Faculty of Medicine. Graduated from Hacettepe University Faculty of Medicine in 2013 with high honors, and in 2018 began residency in Internal Medicine at Hacettepe University, ranking first in the Medical Specialization Examination (TUS). Completed gastroenterology subspecialty training in 2021 and continues doctoral (Ph.D.) studies in Basic Surgical Research at the Hacettepe University Institute of Health Sciences.
Dr. Şimşek completed a 16-month advanced endoscopy and bariatric endoscopy clinical fellowship program at Brigham and Women’s Hospital, affiliated with Harvard Medical School. During this time, specialized in endoscopic submucosal dissection (ESD) and bariatric endoscopy. Also conducted research on liver transplantation and Barrett’s esophagus at Johns Hopkins University, and received advanced endoscopy training at the University of Augsburg with a scholarship from the European Society of Gastrointestinal Endoscopy (ESGE). Served as a visiting researcher at Cleveland Clinic Ohio and Mitera Hospital in Athens. Dr. Şimşek’s research focuses on gastrointestinal diseases, obesity treatment, and liver diseases. In particular, has carried out studies showing superior performance in clinical tasks with an artificial intelligence language model called GastroGPT, and has contributed to the development of new devices for endoscopic weight-loss procedures and endoscopic tumor resection. With more than 100 scientific publications and more than 1,000 citations nationally and internationally, Dr. Şimşek has received awards at various congresses and serves actively on committees of prestigious societies such as the European Society of Gastrointestinal Endoscopy (ESGE), the American Society for Gastrointestinal Endoscopy (ASGE), and United European Gastroenterology (UEG). Dr. Şimşek’s areas of interest include advanced endoscopy (ERCP, EUS, POEM), reflux disease and its treatment, obesity, endoscopic weight-loss procedures (sleeve gastrectomy, gastric balloon), endoscopic treatment of early-stage tumors (ESD), and liver diseases.Publications
Source: Hacettepe University academic database (AVESİS) · All publications (87) ↗
Articles 75
- Artificial intelligence in gastroenterology clinical practice: Scoping review of large language model applicationsInternational Journal of Medical Informatics, cilt.214, 2026 (SCI-Expanded, Scopus)
- Shifts in liver biopsy indications and histopathological diagnoses: A report from a tertiary care center in TürkiyeHepatology Forum, cilt.7, sa.3, ss.262-268, 2026 (Scopus)
- Comparative Performance of Large Language Models on European Gastroenterology Board-Style Questions: Analysis of Reasoning Versus Non-Reasoning ArchitecturesJournal of Clinical Medicine, cilt.15, sa.7, 2026 (SCI-Expanded, Scopus)
- Lack of follow-up in Helicobacter pylori eradication treatment: Results from the European registry on Helicobacter pylori managementWorld Journal of Gastroenterology, cilt.32, sa.7, 2026 (SCI-Expanded, Scopus)
- Higher Doses of Bismuth and Antibiotics Do Not Improve Helicobacter pylori Treatment Effectiveness: Results From the European Registry on Helicobacter pylori ManagementClinical Gastroenterology and Hepatology, 2026 (SCI-Expanded, Scopus)
- Magnets in tiny ducts: magnetic compression anastomosis in the pediatric population — a review of the literature with illustrative casesPediatric Radiology, 2026 (SCI-Expanded, Scopus)
- Commercial real-time PCR kit results for the detection of Helicobacter pylori and clarithromycin resistance in stool samplesINDIAN JOURNAL OF MEDICAL MICROBIOLOGY, cilt.57, 2025 (SCI-Expanded, Scopus)
- Evaluating the Role of Artificial Intelligence in Making Clinical Decisions for Treating Acute PancreatitisJOURNAL OF CLINICAL MEDICINE, cilt.14, 2025 (SCI-Expanded, Scopus)
- Gastroenterology Training and Career in Women: Challenges and OpportunitiesUNITED EUROPEAN GASTROENTEROLOGY JOURNAL, cilt.13, sa.4, ss.650-655, 2025 (SCI-Expanded, Scopus)
- Ascending the "Hill" of Artificial Intelligence in Upper Gastrointestinal EndoscopyUNITED EUROPEAN GASTROENTEROLOGY JOURNAL, cilt.13, sa.4, ss.510-511, 2025 (SCI-Expanded, Scopus)
- Endoscopic Retrograde Cholangiopancre atography in Pediatric Population: A Decade-Long Experience from 2 Tertiary CentersTURKISH JOURNAL OF GASTROENTEROLOGY, cilt.36, sa.5, ss.321-327, 2025 (SCI-Expanded, Scopus, TRDizin)
- Endoscopic retrograde cholangiopancreatography training conditions, results from a pan-European survey: Between vision and realityUNITED EUROPEAN GASTROENTEROLOGY JOURNAL, cilt.13, sa.3, ss.474-487, 2025 (SCI-Expanded, Scopus)
- Astroviruses and celiac disease: a preliminary study into potential environmental triggersActa Medica, 2025 (TRDizin)
- Effect of periampullary diverticulum morphology on ERCP cannulation and clinical resultsSCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, cilt.60, sa.4, ss.292-299, 2025 (SCI-Expanded, Scopus)
- QUAIDE - Quality assessment of AI preclinical studies in diagnostic endoscopyGUT, cilt.74, ss.153-161, 2024 (SCI-Expanded, Scopus)
- Prospective evaluation of patients with non-cirrhotic portal hypertension: A single-centre studyALIMENTARY PHARMACOLOGY & THERAPEUTICS, cilt.60, sa.10, ss.1487-1488, 2024 (SCI-Expanded, Scopus)
- Prevalence of Gastroparesis in Patients With Chronic Pancreatitis and Predictive Factors: A Novel Prediction Model Using Supervised Machine LearningAMERICAN JOURNAL OF GASTROENTEROLOGY, sa.10S, 2024 (SCI-Expanded, Scopus)
- Comparison of ERCP Outcomes and Complication Risk between Elderly and Younger Patients: A Large Single-Center StudyJOURNAL OF CLINICAL MEDICINE, cilt.13, sa.20, 2024 (SCI-Expanded, Scopus)
- Specific Oral Manifestations in Adults with Crohn's DiseaseJOURNAL OF CLINICAL MEDICINE, cilt.13, sa.13, 2024 (SCI-Expanded, Scopus)
- The evolution and revolution of artificial intelligence in hepatology: From current applications to future paradigmsHEPATOLOGY FORUM, cilt.5, sa.3, ss.97-99, 2024 (ESCI, Scopus, TRDizin)
- Inborn Errors of Immunity in Adults with Autoimmune Liver Diseases.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, cilt.35, sa.7, ss.560-567, 2024 (SCI-Expanded, Scopus, TRDizin)
- The frequency and clinical significance of antibodies to soluble liver antigen/liver pancreas in autoimmune hepatitis: a prospective single-center studyEuropean Journal of Gastroenterology and Hepatology, cilt.36, sa.5, ss.652-656, 2024 (SCI-Expanded, Scopus)
- Effectiveness of Helicobacter pylori Treatments According to Antibiotic ResistanceAmerican Journal of Gastroenterology, cilt.119, sa.4, ss.646-654, 2024 (SCI-Expanded, Scopus)
- Commercial Real-Time PCR Kit Results for the Detection of Helicobacter pylori and Clarithromycin Resistance in Stool SamplesResearch Square, 2024 (Hakemli Dergi)
- Comparison of normal saline and antiseptic solution effect on the early peristomal infection rates of patients with percutaneous endoscopic gastrostomy tubes: A randomized double-blind study.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, cilt.38, ss.1343-1353, 2023 (SCI-Expanded, Scopus)
- Ileocecal valve that cannot be intubated in Crohn’s disease: is this a sign of poor prognosis?International Journal of Colorectal Disease, cilt.38, sa.1, 2023 (SCI-Expanded, Scopus)
- Clinical Outcomes of Older Patients with Non-Variceal Upper Gastrointestinal Bleeding Taking Anti-Thrombotic or Non-Steroidal Anti-Inflammatory AgentsThe Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, cilt.34, sa.9, ss.918-924, 2023 (SCI-Expanded, Scopus, TRDizin)
- Gastroplasty with endoscopic myotomy for the treatment of obesityVideoGIE, cilt.8, sa.5, ss.193-195, 2023 (Scopus)
- Novel single-operator through-the-scope traction device for endoscopic submucosal dissection: Outcomes of a multicenter randomized pilot ex-vivo study in trainees with limited endoscopic submucosal dissection experience (with video)DEN Open, cilt.3, sa.1, 2023 (Scopus)
- Transcriptomic Analysis of Hepatitis B Infected Liver for Prediction of Hepatocellular CarcinomaBiology, cilt.12, sa.2, 2023 (SCI-Expanded, Scopus)
- Future Directions for Robotic Endoscopy–Artificial Intelligence (AI), Three-Dimensional (3D) Imaging, and Natural Orifice Transluminal Endoscopic Surgery (NOTES)Techniques and Innovations in Gastrointestinal Endoscopy, cilt.25, sa.1, ss.95-101, 2023 (ESCI, Scopus)
- Practice patterns and considerations in liver transplantation from living donors with high BMI: A reviewHepatology Forum, cilt.4, sa.3, ss.145-149, 2023 (Scopus, TRDizin)
- Training in Endoscopic Submucosal Dissection in the United States: The Current ParadigmGastrointestinal Endoscopy Clinics of North America, cilt.33, sa.1, ss.41-53, 2023 (Scopus)
- Magnetic Resonance Imaging Predictors of Hepatocellular Carcinoma Progression and Dropout in Patients in Liver Transplantation Waiting ListTransplantation Direct, cilt.8, sa.11, 2022 (ESCI, Scopus)
- Empirical Second-Line Therapy in 5000 Patients of the European Registry on Helicobacter pylori Management (Hp-EuReg)Clinical Gastroenterology and Hepatology, cilt.20, sa.10, ss.2243-2257, 2022 (SCI-Expanded, Scopus)
- Novel articulating through-the-scope traction deviceVideoGIE, cilt.7, sa.10, ss.353-357, 2022 (Scopus)
- Characteristics of patients with hepatocellular carcinoma: A multicenter studyHEPATOLOGY FORUM, cilt.3, sa.3, ss.71-76, 2022 (ESCI, Scopus, TRDizin)
- Endoscopic submucosal dissection with ductotomy for the resection of a gastric duplication cyst with a communicating ductVideoGIE, cilt.7, sa.8, ss.280-283, 2022 (Scopus)
- Hepatitis E Virus Prevalence and Associated Risk Factors in High-Risk Groups: A Cross-Sectional StudyTURKISH JOURNAL OF GASTROENTEROLOGY, cilt.33, sa.7, ss.615-624, 2022 (SCI-Expanded, Scopus, TRDizin)
- Practical points that gastrointestinal fellows should know in management of COVID-19WORLD JOURNAL OF CLINICAL CASES, cilt.10, sa.16, ss.5133-5145, 2022 (SCI-Expanded, Scopus)
- Fecal S100A12 in Takayasu arteritis predicts disease activity and intestinal involvementRHEUMATOLOGY INTERNATIONAL, cilt.42, sa.4, ss.737-742, 2022 (SCI-Expanded, Scopus)
- Redetermining the cutoff point of peristomal infection scoring: Methodological researchJOURNAL OF PARENTERAL AND ENTERAL NUTRITION, cilt.46, sa.2, ss.462-468, 2022 (SCI-Expanded, Scopus)
- The Classification of Biliary Strictures ın Patients With Right Lobe Liver Transplant Recipients and Its Relation to Traversing the Stricture With a Guidewire.Transplantation, cilt.106, ss.328-336, 2022 (SCI-Expanded, Scopus)
- An update on usage of high-risk donors in liver transplantationJournal of Clinical Medicine, cilt.11, sa.1, 2022 (SCI-Expanded, Scopus)
- Transoral outlet reduction: could additional sutures cause more harm?ENDOSCOPY, cilt.53, sa.10, ss.1059-1064, 2021 (SCI-Expanded, Scopus)
- Endoscopic sleeve gastroplasty: suturing the gastric fundus does not confer benefitENDOSCOPY, cilt.53, sa.07, ss.727-731, 2021 (SCI-Expanded, Scopus)
- Role of gastrointestinal system on transmission and pathogenesis of SARS-CoV-2WORLD JOURNAL OF CLINICAL CASES, cilt.9, sa.20, ss.5427-5434, 2021 (SCI-Expanded, Scopus)
- Etiology of Cirrhosis in Turkey: A National Cohort StudyJOURNAL OF HEPATOLOGY, cilt.75, 2021 (SCI-Expanded, Scopus)
- Adverse Event Profile During the Treatment of Helicobacter pylori: A Real-World Experience of 22,000 Patients From the European Registry on H. pylori Management (Hp-EuReg)AMERICAN JOURNAL OF GASTROENTEROLOGY, cilt.116, sa.6, ss.1220-1229, 2021 (SCI-Expanded, Scopus)
- Artificial intelligence method to predict overall survival of hepatocellular carcinomaHepatology Forum, cilt.2, sa.2, ss.64-68, 2021 (Scopus)
- Comprehensive clinicopathologic characteristics of intraabdominal neurogenic tumors: Single institution experience.World journal of clinical cases, cilt.9, ss.2218-2227, 2021 (SCI-Expanded, Scopus)
- Artificial Intelligence to Predict Esophageal Varices in Patients with CirrhosisAcıbadem Üniversitesi Sağlık Bilimleri Dergisi, cilt.12, ss.625-629, 2021 (TRDizin)
- V600E and Non-V600E BRAF Mutations in Colorectal Cancer: Clinicopathologic Correlations in a Single InstitutionUHOD-ULUSLARARASI HEMATOLOJI-ONKOLOJI DERGISI, cilt.31, sa.1, ss.43-49, 2021 (SCI-Expanded, Scopus, TRDizin)
- Lack of Awareness of Hepatitis B Screening and Vaccination in High-Risk Groups.Turkish journal of medical sciences, cilt.51, ss.1229-1233, 2021 (SCI-Expanded, Scopus, TRDizin)
- Feasibility of telehealth in the management of autoimmune hepatitis before and during the COVID-19 pandemicEXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY, cilt.14, sa.12, ss.1215-1219, 2020 (SCI-Expanded, Scopus)
- Anatomical Configuration of the Stomach Post-Endoscopic Sleeve Gastroplasty (ESG)-What Are the Sutures Doing?OBESITY SURGERY, cilt.30, sa.5, ss.2056-2060, 2020 (SCI-Expanded, Scopus)
- Gut microbiota and cancer immunotherapy: prognostic and therapeutic implicationsFUTURE ONCOLOGY, cilt.16, sa.9, ss.497-506, 2020 (SCI-Expanded, Scopus)
- Cryoballoon ablation for gastric pouch and/or outlet reduction in patients with weight regain post Roux-en-Y gastric bypassENDOSCOPY, cilt.52, sa.3, ss.227-230, 2020 (SCI-Expanded, Scopus)
- Considering the first randomized trial of peroral endoscopic myotomy versus surgical myotomy for achalasiaTURKISH JOURNAL OF GASTROENTEROLOGY, cilt.31, sa.2, ss.190-192, 2020 (SCI-Expanded, Scopus, TRDizin)
- Update on liver transplantation-newer aspectsTURKISH JOURNAL OF MEDICAL SCIENCES, cilt.50, ss.1642-1650, 2020 (SCI-Expanded, Scopus, TRDizin)
Conference papers 10
- ENDOSCOPIC MANAGEMENT OF SLEEVE STENOSIS AFTER LAPAROSCOPIC SLEEVE GASTRECTOMY: A 10-YEAR RETROSPECTIVE ANALYSIS OF OUTCOMES, EFFICACY, AND SAFETYDigestive Disease Week (DDW), Washington, Kiribati, 18 - 21 Mayıs 2024, (Özet Bildiri)
- Hepatitis B virus screening and immunization rates in special risk groups.World Congress of Gastroenterology 2019, 21 - 24 Eylül 2019, (Özet Bildiri)
- Hepatitis E virus epidemiology of patients with chronic hepatitis C in TurkeyWorld Congress of Gastroenterology 2019, 21 - 24 Eylül 2019, (Özet Bildiri)
- Sepsis İç hastalıkları servislerindeki en önemli mortalite nedeni17. Ulusal İç Hastalıkları Kongresi, Antalya, Türkiye, 14 - 18 Ekim 2015, ss.105
- Üniversite Öğrencilerinde Karaciğer Hastalıklarına Yönelik Damgalayıcı Tutumlar
- Fonksiyonel Kabızlıkta Abdominal Masaj ile Birlikte Aerobik Egzersiz Eğitiminin Etkileri: Randomize Kontrollü Çalışma
- Karaciğer Sağlığı Bilgi ve Farkındalık Düzeyi
- MULTI-AGENT LLM APPROACH VERSUS SINGLE MODEL IN THE MANAGEMENT OF NON-VARICEAL UPPER GASTROINTESTINAL BLEEDING
- ROLE OF NUCLEAR RECEPTOR COACTIVATOR 4 (NCOA4) GENE VARIANTS IN METABOLIC HYPERFERRITINEMIA OBSERVED IN METABOLIC DYSFUNCTION-ASSOCIATED STEATOHEPATITIS (MASH)
- Fonksiyonel Kabızlıkta Abdominal Masaj ile Birlikte Aerobik Egzersiz Eğitiminin Etkileri: Randomize Kontrollü Çalışma
Kitaplar 2
- Kolorektoanal Problemlerde Farmakolojik Tedavi"Multidisipliner Balış Temeli" ile Pelvik Sağlıkta Fizyoterapi ve Rehabilitasyon, Türkan Albayrak, Serap özgül, Ceren Gürşen, Editör, Hedef Yayıncılık ve Mühendislik, Ankara, ss.249-258, 2023
- PATOFİZYOLOJİNİN TEMELLERİPALME YAYINCILIK, 2017
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- Gastroenterology, Adult Hospital
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