About
She graduated from Hacettepe University Faculty of Medicine in 1995 as the top student of her class. She completed her specialty training in the Department of Psychiatry, Hacettepe University Faculty of Medicine, between 1995 and 2000. Between 2001 and 2002, she received subspecialty training in Clinical Psychopharmacology in the Psychopharmacology division of the Department of Psychiatry, Vanderbilt University School of Medicine. In 2002, she began working as a lecturer in the Department of Psychiatry, Hacettepe University Faculty of Medicine, and became an associate professor in 2006. In 2009, she completed her doctorate in Basic Neurological Sciences at the Hacettepe University Institute of Neurological Sciences and Psychiatry. She became a professor in 2011. She received the İhsan Doğramacı Science Award in 1995, the NARSAD (National Alliance For Research on Schizophrenia and Depression) Young Investigator Award in the USA in 2002, the TÜBİTAK Brain Research Society Research Project Encouragement Award in 2003, the European College of Neuropsychopharmacology (ECNP) Research Award in 2006, and in 2012 the first-place poster award at the European Congress of Psychiatry.
Education
- 2000PsychiatryHacettepe University Faculty of Medicine
- 2009PhD — Basic Neurological SciencesHacettepe University Institute of Neurological Sciences and Psychiatry
- 2000MSc — PsychiatryHacettepe University Faculty of Medicine
- 1995Faculty of MedicineHacettepe University
- 1989TED Ankara College Private High School
Expertise
Publications
Source: Hacettepe University academic database (AVESİS) · All publications (89) ↗
Articles 64
- Autonomic Flexibility and Early Treatment Success: Heart Rate Variability Predicts Remission in First-Episode PsychosisSchizophrenia Bulletin, cilt.52, sa.5, 2026 (SCI-Expanded, SSCI, Scopus)
- İnsan-bilgisayar etkileşimi kullanılarak insan niyetinin tespiti ve yeniden şekillendirilmesiAfyon Kocatepe Üniversitesi Fen ve Mühendislik Bilimleri Dergisi, cilt.26, sa.3, ss.626-640, 2026 (TRDizin)
- Remission of auditory verbal hallucinations following neuronavigated, personalized rTMS guided by EEG, MRI, and auditory evoked potentials: A case reportPsychiatry Research Case Reports, cilt.5, sa.1, 2026 (Scopus)
- Intention mining and intention reshaping: surfacing deep intentions by proactive visuals to morph them into new intentionsExpert Systems with Applications, cilt.300, 2026 (SCI-Expanded, Scopus)
- Exploring Cognitive Enhancements and Default Mode Network Connectivity in Relapsing-Remitting Multiple Sclerosis: Insights from a Prospective Study Investigating the MIND DietMULTIPLE SCLEROSIS JOURNAL, sa.3, ss.544, 2024 (SCI-Expanded, Scopus)
- A systematic chart review of pharmacological interventions in patients with clozapine-induced hypersalivation.Schizophrenia research, cilt.268, ss.138-144, 2024 (SCI-Expanded, SSCI, Scopus)
- Eighteen years of the medical scientist training program at Hacettepe UniversityActa Medica, cilt.55, sa.1, ss.29-36, 2024 (TRDizin)
- The Role of Cannabis in the Development of PsychosisTURK PSIKIYATRI DERGISI, cilt.35, sa.3, ss.234-244, 2024 (SSCI, Scopus)
- Effects of Clozapine on Cortical InhibitionJOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, cilt.44, sa.1, ss.16-24, 2024 (SCI-Expanded, Scopus)
- Comprehensive dissection of prevalence rates, sex differences, and blood level-dependencies of clozapine-associated adverse drug reactionsPsychiatry Research, cilt.330, 2023 (SCI-Expanded, SSCI, Scopus)
- Hodgkin Lymphoma in Patients Receiving Clozapine Treatment: 2 Case Reports and Literature Review.Journal of clinical psychopharmacology, cilt.43, sa.2, ss.180-183, 2023 (SCI-Expanded, Scopus)
- A diffusion tensor imaging study in schizophrenia patients with clozapine induced obsessive compulsive symptomsHUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL, cilt.38, 2023 (SCI-Expanded, Scopus)
- Effect of clozapine on suicidality in patients with schizophrenia at a university hospital in TurkeySchizophrenia Research, 2023 (SCI-Expanded, SSCI, Scopus)
- Valproate, obesity and other causes of clozapine poor metabolism in the context of rapid titration may explain clozapine-induced myocarditis: A re-analysis of a Turkish case series El valproato, la obesidad y otras causas de metabolismo deficiente de la clozapina en el contexto de una titulación rápida de las dosis pueden explicar la miocarditis inducida por clozapina: un nuevo análisis de una serie de casos turcaRevista de Psiquiatria y Salud Mental, cilt.15, sa.4, ss.281-286, 2022 (SCI-Expanded, SSCI, Scopus)
- Combination With Long-Acting Injectable Antipsychotics and Utilization of Nonstandard Formulations as Compliance Enhancing Methods for Clozapine Users A Systematic Review and A Case SeriesJOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, cilt.42, sa.3, ss.298-307, 2022 (SCI-Expanded, SSCI, Scopus)
- Renal effects of long-term lithium therapy, revisitedHUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL, cilt.37, sa.2, 2022 (SCI-Expanded, Scopus)
- Effects of the COVID -19 pandemic on patients with schizophrenia spectrum disorders.Acta Medica, 2022 (TRDizin)
- The cognitive aspect of formal thought disorder and its relationship with global social functioning and the quality of life of in schizophreniaSOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY, cilt.56, ss.1399-1410, 2021 (SCI-Expanded, SSCI, Scopus)
- Common Side Effects and Metabolic Syndrome due to Clozapine: Relationship with the Clinical Variables and DisabilityTURK PSIKIYATRI DERGISI, cilt.32, sa.2, ss.87-99, 2021 (SSCI, Scopus, TRDizin)
- Augmentation of Clozapine Due to Inadequate Treatment Response in Schizophrenia: Comparison of Patients with Augmented and Non-augmented TreatmentsTURK PSIKIYATRI DERGISI, cilt.32, sa.1, ss.1-7, 2021 (SSCI, Scopus, TRDizin)
- All in One Clozapine-Associated Acute Pancreatitis With Multiple Organ InvolvementJOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, cilt.41, sa.2, ss.214-216, 2021 (SCI-Expanded, Scopus)
- A comparative study of detection of myocarditis induced by clozapine: With and without cardiac monitoringPsychiatry Research, cilt.279, ss.90-97, 2019 (SCI-Expanded, SSCI, Scopus)
- Examination of formal thought disorder and its clinical correlates with the Turkish Version of the Thought and Language Disorder Scale (TALD-TR) in schizophreniaComprehensive Psychiatry, cilt.93, ss.7-13, 2019 (SCI-Expanded, SSCI, Scopus)
- The Relationship of the Change in Symptoms and Cognitive Functions With the Change in Cortical Inhibition Parameters Measured by Transcranial Magnetic Stimulation: An Eight-Week Follow-Up StudyTURK PSIKIYATRI DERGISI, cilt.26, sa.3, ss.161-171, 2015 (SSCI, Scopus, TRDizin)
- Effect of clozapine on white matter integrity in patients with schizophrenia: A diffusion tensor imaging studyPSYCHIATRY RESEARCH-NEUROIMAGING, cilt.223, sa.3, ss.226-235, 2014 (SCI-Expanded, Scopus)
- Language-dependent performance on the letter fluency task in patients with schizophreniaSCHIZOPHRENIA RESEARCH, cilt.152, ss.421-429, 2014 (SCI-Expanded, SSCI, Scopus)
- Language dependent performance on the letter fluency task in patients with schizophreniaSchizophrenia Research, cilt.152, ss.421-429, 2014 (SCI-Expanded, SSCI, Scopus)
- Effects of Acute and Chronic Electroconvulsive Shocks on Glycogen Synthase Kinase 3[beta] Level and Phosphorylation in MiceJOURNAL OF ECT, cilt.29, sa.4, ss.261-266, 2013 (SCI-Expanded, SSCI, Scopus)
- Formulation and evaluation of clozapine orally disintegrating tablets prepared by direct compressionPHARMAZIE, cilt.68, sa.2, ss.110-116, 2013 (SCI-Expanded, Scopus)
- Differential effects of antipsychotics on hippocampal presynaptic protein expressions and recognition memory in a schizophrenia model in micePROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, cilt.39, sa.1, ss.62-68, 2012 (SCI-Expanded, Scopus)
- Psychiatric Disorders and EpigeneticsTURK PSIKIYATRI DERGISI, cilt.23, sa.2, ss.130-140, 2012 (SSCI, Scopus, TRDizin)
- The influence of N-desmethylclozapine and clozapine on recognition memory and BDNF expression in hippocampusBRAIN RESEARCH BULLETIN, cilt.84, sa.2, ss.144-150, 2011 (SCI-Expanded, Scopus)
- The prevalence and clinical correlates of metabolic syndrome in patients with schizophrenia: findings from a cohort in TurkeyEUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE, cilt.261, sa.1, ss.69-78, 2011 (SCI-Expanded, Scopus)
- Orally disintegrating tablets ii: In vitro and in vivo evaluations Aǧızda daǧılan tabletler ii: In vitro ve in vivo deǧerlendirilmeleriHacettepe University Journal of the Faculty of Pharmacy, cilt.31, sa.1, ss.59-70, 2011 (Scopus)
- Effects of Self-Image on Identity Status Among Turkish AdolescentsADOLESCENT PSYCHIATRY, cilt.1, sa.1, ss.88-93, 2011 (SSCI, ESCI)
- Antipsikotiklerin Kardiyak Yan EtkileriPsikiyatride Güncel, cilt.1, ss.251-265, 2011 (Hakemli Dergi)
- Orally disintegrating tablets i: Preparation technologies Aǧizda daǧilan tabletler i: Hazirlama teknolojileriHacettepe University Journal of the Faculty of Pharmacy, cilt.30, sa.2, ss.205-230, 2010 (Scopus)
- Anemia and Neutropenic Fever with High Dose Diazoxide Treatment in a Case with Hyperinsulinism Due to Munchausen by ProxyJOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, cilt.23, sa.7, ss.719-723, 2010 (SCI-Expanded, Scopus)
- Evaluation of SISCOM in routine regional cerebral blood flow alterations after clozapine, in schizophreniaHELLENIC JOURNAL OF NUCLEAR MEDICINE, cilt.13, sa.1, ss.35-39, 2010 (SCI-Expanded, Scopus)
- The effect of clozapine on regional cerebral blood flow and brain metabolite ratios in schizophrenia: Relationship with treatment responsePSYCHIATRY RESEARCH-NEUROIMAGING, cilt.174, sa.2, ss.121-129, 2009 (SCI-Expanded, Scopus)
- Neuroimaging Findings in Autism: A Brief ReviewTURK PSIKIYATRI DERGISI, cilt.20, sa.2, ss.164-174, 2009 (SSCI, Scopus, TRDizin)
- Semantic memory deficits based on category fluency performance in schizophrenia: Similar impairment patterns of semantic organization across Turkish and Japanese patientsPSYCHIATRY RESEARCH, cilt.167, ss.47-57, 2009 (SCI-Expanded, SSCI, Scopus)
- Evoked Potentials and regional cerebral blood flow changes in conversion disorder: A case report and reviewTURK PSIKIYATRI DERGISI, cilt.19, sa.1, ss.101-107, 2008 (SSCI, Scopus, TRDizin)
- A randomized double blind comparison of clozapine and high doseolanzapine in treatment resistant patients with schizophreniaJOURNAL OF CLINICAL PSYCHIATRY, cilt.69, ss.274-285, 2008 (SCI-Expanded, SSCI, Scopus)
- A randomized, double-blind comparison of clozapine and high-dose olanzapine in treatment-resistant patients with schizophreniaJOURNAL OF CLINICAL PSYCHIATRY, cilt.69, sa.2, ss.274-285, 2008 (SCI-Expanded, SSCI, Scopus)
- Platelet and Plasma Serotonin Levels and Platelet Monoamine Oxidase Activity in Patients with Major Depression: Effects of Sertraline TreatmentTURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.33, sa.3, ss.97-103, 2008 (SCI-Expanded, TRDizin)
- The effect of clozapine on neuroimaging findings in schizophreniaPSYCHIATRIA DANUBINA, cilt.19, sa.4, ss.367-369, 2007 (SCI-Expanded, Scopus)
- Influence of clozapine on platelet serotonin, monoamine oxidase and plasma serotonin levelsPSYCHIATRY RESEARCH, cilt.149, ss.49-57, 2007 (SCI-Expanded, SSCI, Scopus)
- Obsessive compulsive symptoms associated with quetiapine treatment in a schizophrenic patient: A case reportPROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, cilt.30, sa.4, ss.724-727, 2006 (SCI-Expanded, Scopus)
- The neurobiology of hallucinationsTURK PSIKIYATRI DERGISI, cilt.16, sa.4, ss.268-275, 2005 (SSCI, Scopus, TRDizin)
- Depresyon araştırmalarında kullanılan hayvan modelleriKlinik Psikiyatri Dergisi, cilt.8, sa.3, ss.123-134, 2005 (TRDizin)
- Clozapine-induced tardive dyskinesia: A case reportPROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, cilt.29, sa.4, ss.633-635, 2005 (SCI-Expanded, Scopus)
- Obsessive-compulsive symptoms in clozapine-treated schizophrenic patientsPSYCHIATRY AND CLINICAL NEUROSCIENCES, cilt.59, sa.2, ss.219-222, 2005 (SCI-Expanded, Scopus)
- Creutzfeldt-Jakob disease: A case that initiated with psychiatric symptomsTURK PSIKIYATRI DERGISI, cilt.16, sa.1, ss.55-59, 2005 (SSCI, Scopus, TRDizin)
- Creutzfeldt Jakob disease A case that initiated with psychiatricsymptomsTURK PSIKIYATRI DERGISI, cilt.16, ss.55-59, 2005 (SCI-Expanded, Scopus, TRDizin)
- A double blind controlled study of adjunctive treatment with risperidonein schizophrenic patients partially responsive to clozapine Efficacyand safetyJOURNAL OF CLINICAL PSYCHIATRY, cilt.66, ss.63-72, 2005 (SCI-Expanded, SSCI, Scopus)
- A double-blind controlled study of adjunctive treatment with risperidone in schizophrenic patients partially responsive to clozapine: Efficacy and safetyJOURNAL OF CLINICAL PSYCHIATRY, cilt.66, sa.1, ss.63-72, 2005 (SCI-Expanded, SSCI, Scopus)
- Psychopathology and personality features in orthopedic patients with boxer's fracturesGENERAL HOSPITAL PSYCHIATRY, cilt.27, sa.1, ss.13-17, 2005 (SCI-Expanded, SSCI, Scopus)
- Venous thromboembolism and escitalopramGENERAL HOSPITAL PSYCHIATRY, cilt.26, sa.6, ss.481-483, 2004 (SCI-Expanded, SSCI, Scopus)
- A Comparison of Incidence of Diabetes Mellitus Between Atypical Antipsychotic Drugs A Survey for Clozapine Risperidone Olanzapine and QuetiapineJournal of Clinical Psychopharmacology, cilt.24, ss.345-348, 2004 (SCI-Expanded, Scopus)
Conference papers 25
- Imaging findings in patients with clozapine associated obsessive compusive disorders27 th European Congress of Psychiatry, Varşova, Polonya, 6 - 09 Nisan 2019, cilt.56, ss.230, (Özet Bildiri)
- EXAMINATION OF FORMAL THOUGHT DISORDER AND ITS CLINICAL CORRELATES WITH THE TURKISH VERSION OF THE THOUGHT AND LANGUAGE DISORDER SCALE (TALD-TR) IN SCHIZOPHRENIACongress of the Schizophrenia-International-Research-Society (SRIS), Florida, Amerika Birleşik Devletleri, 10 - 14 Nisan 2019, cilt.45, (Özet Bildiri)
- Psikiyatri Servisine Yatırılarak Klozapin Başlanan Hastaların Sosyodemografik ve Klinik Özellikleri ve İlacın Kesilmesine Neden Olan Yan Etkiler.54. Ulusal Psikiyatri Kongresi, Ankara, Türkiye, 2 - 06 Ekim 2018, cilt.29, ss.118, (Özet Bildiri)
- A major challenge for clinicians: discussing rechallenge with clozapine through a case seriesEUROPEAN NEUROPSYCHOPHARMACOLOGY, Paris, Fransa, 2 - 05 Eylül 2017, cilt.27, ss.961, (Özet Bildiri)
- Effect of clozapine on psychiatric comorbidities in patients with schizophreniaEUROPEAN PSYCHIATRY, 1 - 30 Nisan 2017, cilt.41, ss.197, (Özet Bildiri)
- Side effects of clozapine and their relationship with clinical variables in patients with schizophreniaEUROPEAN PSYCHIATRY, 1 - 30 Nisan 2017, cilt.41, ss.197, (Özet Bildiri)
- SWITCHING TO CLOZAPINE TREATMENT IN PATIENTS WITH SCHIZOPHRENIA: THE CLINICAL COURSE, REMISSION, AND AUGMENTATION OF TREATMENT AFTER THE SWITCHSCHIZOPHRENIA BULLETIN, San Diego, 24 - 28 Mart 2017, cilt.43, ss.202, (Özet Bildiri)
- Yüksek Klozapin Kan Düzeyine Rağmen Toksisite Belirtisi Görülmeyen Bir Olgu50. Ulusal Psikiyatri Kongresi, Türkiye, 12 - 16 Kasım 2014, cilt.25
- Yüksek klozapin kan düzeyi ve toksisite ilişkisi Bir olgu serisiTPD 18. Yıllık Toplantı ve Klinik Eğitim Sempozyumu, Türkiye, 23 - 26 Nisan 2014
- İnhale eroin bağımlılığında yoksunluk antipsikotik tedavi ve deliryum gelişimi iki olgu sunumu18. TPD Yıllık Toplantı ve Klinik Eğitim Sempozyumu, Antalya, Türkiye, 23 - 26 Nisan 2014, cilt.25, ss.30
- Yüksek Klozapin Kan Düzeyi ve Toksisite İlişkisi Bir Olgu Serisi18.Yıllık Klinik Eğitim Sempozyumu, Türkiye, 23 Nisan 2014
- Klozapin tedavisinin beşinci yılında ortaya çıkan tardif diskinezi tardif nokturnal akatizi ve tardif okülojiik distonik12.Türk Psikiyatri Dergi Yıllık Klinik Eğitim Sempozyumu, Türkiye, 23 - 27 Nisan 2008
- The influence of clozapine treatment on plasma levels of reactive oxygen species and antioxidant enzymes in patients with schizophrenia32nd FEBS Congress, Viyana, Avusturya, 7 - 12 Temmuz 2007, cilt.274, ss.283
- Effects of Clozapine on Regional Cerebral Blood Flow in Patients with Schizophrenia Relationship with Neurocognitive Functions and Response to TreatmentWorld Psychiatry Association International Congress, İstanbul, Türkiye, 12 - 16 Temmuz 2006, cilt.17, ss.305
- Şizofreni hastalarında klozapinin beyin kan akımı üzerine etkisi bilişsel işlevler ve tedaviye yanıtla ilişkisi1. Ulusal Psikofarmakoloji Kongresi, İstanbul, Türkiye, 14 - 17 Aralık 2005
- Clozapine effect on rCBF in patients with treatment refractory schizophrenic patientsAnnual Congress of the European Associaton of Nuclear Medicine, İstanbul, Türkiye, 15 - 19 Ekim 2005, cilt.32, ss.194
- Morphing Detected Human Intention Via Human-Computer Interactions
- Clozapine and Long-Acting Injectable Antipsychotic Combination: A Retrospective Chart Review.
- Effects of Clozapine on Cortical Inhibition
- Klozapinin uzun etkili enjekte edilebilir antipsikotiklerle kombinasyonu
- Effect of clozapine on suicidality in patients with schizophrenia.
- Effects of the COVID-19 pandemic on patients with schizophrenia spectrum disorders
- İNTRAVENÖZ EROİN KULLANIM BOZUKLUĞUNA EŞLİK EDEN TROpİKAMİD KÖTÜYE KULLANIMI
- İnhale Eroin Bağımlılığında Yoksunluk Antipsikotik Tedavi ve Deliryum Gelişimi İki Olgu Sunumu
- The effect of diazepam on performance of mice in forced swimming test
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